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Setia Kangen Water Bali Dan Kesehatan Jantung

 

  

 

Serangan jantung (dalam dunia medis dikenal infark miokard) merupakan suatu keadaan pasokan darah menuju ke jantung mengalami hambatan.  

 

Ini adalah kondisi medis darurat karena adanya penggumpalan darah atau penumpukan lemak, kolesterol, dan unsur lainnya.  

 

Gangguan aliran darah ini bisa merusak atau menghancurkan otot jantung yang bisa fatal akibatnya. 

 

Seperti yang dikutip dari alodokter.com, serangan jantung tidak tergantung pada kondisi tingkat keparahan sakit dada yang dirasakan.  

 

Sakit dada belum tentu terjadi pada semua orang yang sakit jantung. 

Terkadang rasa sakitnya ringan, seperti sakit lambung, dan Sebaliknya, tidak semua sakit dada adalah akibat dari serangan yang terjadi.  

 

Karenanya, waspadai gejala yang umum terjadi, yaitu : 

 

– Terasa sakit atau nyeri dada  

 

– Sangat gelisah atau cemas  

 

– Sesak nafas  

 

– Merasa lemah dan pusing 

 

  

 

 

Pemulihan dan Peluang Hidup Setelah Serangan Jantung 

 

Pasien yang mengalami serangan bisa pulih seperti sediakala tergantung kepada tingkat kerusakan otot jantung yang terjadi.
Bisa beberapa minggu, ada yang membutuhkan waktu beberapa bulan. 

 

Cara mengurangi risiko terulangnya serangan jantung, yakni dengan cara merubah gaya hidup, termasuk di antaranya cara makanan dan konsumsi obat-obatan.
Mengembalikan kebugaran fisik, agar bisa kembali melakukan aktivitas sesuai kebutuhan Anda.  

 

 

 

Peluang hidup seseorang yang pernah mengalami serangan Jantung:   

 

 

Pertama, sangat bergantung pada usia pasien.  

 

Apabila usia orang yang mengalami gangguan jantung makin tua, kemungkinan terjadinya komplikasi akan bertambah.
Kedua, tingkat keparahan gangguan jantung juga berpengaruh.  

 

Yang paling utama adalah seberapa parah kerusakan otot jantung yang terjadi.
Ketiga, waktu yang dibutuhkan seseorang hingga dia mendapatkan pertolongan saat mengalami serangan jantung.  

 

Makin lama penanganan gangguan jantung, maka peluang hidupnya akan makin kecil. 

 

 

 

 

 

 

 

 

Manfaat Air Hidrogen Setelah Serangan Jantung: 

 

Serangan jantung selalu dikaitkan dengan cedera iskemik reperfusi di berbagai organ termasuk otak dan jantung.  

 

Molekul hidrogen H2 sebagai antioksidan baru yang berpotensi membantu proses pemulihan setelah serangan.  

 

Penelitian kali ini menguji hipotesis bahwa inhalasi gas H2 yang dimulai pada awal resusitasi kardiopulmoner (CPR) dapat memperbaiki akibat serangan jantung yang diuji pada tikus percobaan. 

 

Hasil penelitian, inhalasi gas hidrogen menghasilkan peningkatan yang lebih baik dalam bertahan hidup dan skor defisit neurologis (NDS) setelah ROSC sebanding dengan hipotermia terapeutik.  

 

Inhalasi gas hidrogen mencegah kenaikan tekanan diastolik ventrikel kiri dan peningkatan kadar IL-6 serum setelah ROSC. 

 

Kesimpulannya, molekul H2 merupakan strategi yang baik untuk mengurangi angka kematian dan hasil fungsional sindrom pasca-CA pada model tikus percobaan, baik sendiri atau dikombinasikan dengan pengobatan hipotermia terapeutik. 

 

Berikut ini white paper laporan resmi hasil pengujian yang dikutip langsung dari jaha.ahajournals.org

 

 

 

 

Background: 

All clinical and biological manifestations related to postcardiac arrest (CA) syndrome are attributed to ischemia–reperfusion injury in various organs including brain and heart. Molecular hydrogen (H2) has potential as a novel antioxidant. This study tested the hypothesis that inhalation of H2 gas starting at the beginning of cardiopulmonary resuscitation (CPR) could improve the outcome of CA. 

 

 

 

Methods and Results: 

Ventricular fibrillation was induced by transcutaneous electrical epicardial stimulation in rats. After 5 minutes of the subsequent CA, rats were randomly assigned to 1 of 4 experimental groups at the beginning of CPR: mechanical ventilation (MV) with 2% N2 and 98% O2 under normothermia (37°C), the control group; MV with 2% H2 and 98% O2 under normothermia; MV with 2% N2 and 98% O2 under therapeutic hypothermia (TH), 33°C; and MV with 2% H2 and 98% O2 under TH. Mixed gas inhalation and TH continued until 2 hours after the return of spontaneous circulation (ROSC). H2 gas inhalation yielded better improvement in survival and neurological deficit score (NDS) after ROSC to an extent comparable to TH. H2 gas inhalation, but not TH, prevented a rise in left ventricular end-diastolic pressure and increase in serum IL-6 level after ROSC. The salutary impact of H2 gas was at least partially attributed to the radical-scavenging effects of H2 gas, because both 8-OHdG- and 4-HNE-positive cardiomyocytes were markedly suppressed by H2 gas inhalation after ROSC. 

 

 

Conclusions: 

Inhalation of H2 gas is a favorable strategy to mitigate mortality and functional outcome of post-CA syndrome in a rat model, either alone or in combination with TH. 

 

Kumpulan Penelitian Jantung dari Air Alkali Kaya Hidrogen. 

 

304.Hayashida, K., et al., Inhalation of hydrogen gas protects the heart from ischemic reperfusion injury. Journal of the American College of Cardiology, 2008. 51(10): p. A375-A375. K., et al., Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. Journal of Cardiac Failure, 2008. 14(7): p. S168-S168. 

 

351.Xin, H.G., et al., Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats. Mol Cell Biochem, 2014. 392(1-2): p. 117-24. 

 

352.Zhu, W.J., et al., Amelioration of cardio-renal injury with aging in dahl salt-sensitive rats by H2-enriched electrolyzed water. Med Gas Res, 2013. 1): p. 26. 

 

324.Nakao, A., et al., Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2010. 29(5): p. 544-53. 

 

325.Noda, K., et al., A novel method of preserving cardiac grafts using a hydrogen-rich water bath. Journal of Heart and Lung Transplantation, 2013. 32(2): p. 241-50. 

 

327.Sun, Q., et al., Hydrogen-Rich Saline Protects Myocardium Against Ischemia/Reperfusion Injury in Rats.Experimental Biology and Medicine, 2009. 234(10): p. 1212-1219. 

 

328.Tan, M., et al., Hydrogen as additive of HTK solution fortifies myocardial preservation in grafts with prolonged cold ischemia. International Journal of Cardiology, 2013. 167(2): p. 383-90. 

 

332.Zhang, Y., et al., Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. International Journal of Cardiology, 2011. 148(1): p. 91-5 

 

337.Zhu, W.J., et al., Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats. Nephrology, Dialysis, Transplantation, 2011. 26(7): p. 2112-8. 

 

244.Fujii, Y., et al., Insufflation of hydrogen gas restrains the inflammatory response of cardiopulmonary bypass in a rat model. Artif Organs, 2013. 37(2): p. 136-41. 

 

245.Hayashi, T., et al., Inhalation of hydrogen gas attenuates left ventricular remodeling induced by intermittent hypoxia in mice. American Journal of Physiology – Heart and Circulatory Physiology, 2011. 301(3): p. H1062-9. 

 

246.Hayashida, K., et al., H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model. J Am Heart Assoc, 2012. 1(5): p. e003459. 

 

247.Hayashida, K., et al., Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest, Independent of Targeted Temperature Management. Circulation, 2014. 

 

248.Huo, T.T., et al., Hydrogen-Rich Saline Improves Survival and Neurological Outcome after Cardiac Arrest and Cardiopulmonary Resuscitation in Rats. Anesth Analg, 2014. 

 

249.Jing, L., et al., Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats. Heart Lung Circ, 2014. 

 

251.Nagatani, K., et al., The Effect of Hydrogen Gas on a Mouse Bilateral Common Carotid Artery Occlusion. Brain Edema XVActa Neurochirurgica Supplement 2013. 

 

252.Noda, K., et al., Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. Transpl Int, 2012. 25(12): p. 1213-22. 

 

253.Qin, Z.X., et al., Hydrogen-rich saline prevents neointima formation after carotid balloon injury by suppressing ROS and the TNF-alpha/NF-kappaB pathway. Atherosclerosis, 2012. 220(2): p. 343-50. 

 

254.Sakai, K., et al., Inhalation of hydrogen gas protects against myocardial stunning and infarction in swine.Scandinavian Cardiovascular Journal, 2012. 46(3): p. 183-9. 

 

255.Shinbo, T., et al., Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart. Am J Physiol Heart Circ Physiol, 2013. 305(4): p. H542-50. 

 

256.Sun, Q., et al., Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.Cardiovasc Res, 2012. 94(1): p. 144-53. 

 

257.Wu, S., et al., Hydrogen-containing saline attenuates doxorubicin-induced heart failure in rats. Pharmazie, 2014. 69(8): p. 633-6. 

 

258.Xie, Q., et al., Hydrogen gas protects against serum and glucose deprivation induced myocardial injury in H9c2 cells through activation of the NFE2 related factor 2/heme oxygenase 1 signaling pathway. Mol Med Rep, 2014. 10(2): p. 1143-9. 

 

259.Yoshida, A., et al., H(2) mediates cardioprotection via involvements of K(ATP) channels and permeability transition pores of mitochondria in dogs. Cardiovasc Drugs Ther, 2012. 26(3): p. 217-26. 

 

260.Zhang, G., et al., Pharmacological postconditioning with lactic Acid and hydrogen rich saline alleviates myocardial reperfusion injury in rats. Sci Rep, 2015. 5: p. 9858. 

 

180.Chang, W.J. and L.H. Toledo-Pereyra, The potential benefits of hydrogen-rich saline in ischemia and reperfusion injury. Journal of Surgical Research, 2013. 180(2): p. 248-9. 

 

218.Qian, L., et al., The potential cardioprotective effects of hydrogen in irradiated mice. J Radiat Res, 2010. 51(6): p. 741-7. 

 

174.Suzuki, Y., et al., Are the effects of alpha-glucosidase inhibitors on cardiovascular events related to elevated levels of hydrogen gas in the gastrointestinal tract? FEBS Letters, 2009. 583(13): p. 2157-9. 

 

48.Huang, G., et al., The neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest. Resuscitation, 2013. 84(5): p. 690-5. 

 

391. Qiu, X.C., et al., [Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation]. Zhonghua Shao Shang Za Zhi, 2010. 26(6): p. 435-8. 

 

457.Sakai, T., et al., Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. Vasc Health Risk Manag, 2014. 10: p. 591-7. 

 

459.Wang, W.N., et al., [Regulative effects of hydrogen-rich medium on monocytic adhesion and vascular endothelial permeability]. Zhonghua Yi Xue Za Zhi, 2013. 93(43): p. 3467-9. 

 

405.Chao, Y.C. and M.T. Chiang, Effect of alkaline reduced water on erythrocyte oxidative status and plasma lipids of spontaneously hypertensive rats. Taiwanese Journal of Agricultural Chemistry and Food Science, 2009. 47(2): p. 71-72. 

 

407.Chen, Y., et al., Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways. International Journal of Molecular Medicine, 2013. 31(3): p. 597-606. 

 

410.Ekuni, D., et al., Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model. Arch Oral Biol, 2012. 57(12): p. 1615-22. 

 

417.He, B., et al., Protection of oral hydrogen water as an antioxidant on pulmonary hypertension. Mol Biol Rep, 2013. 40(9): p. 5513-21. 

 

432.Nishioka, S., et al., Effect of hydrogen gas inhalation on lipid metabolism and left ventricular remodeling induced by intermittent hypoxia in mice. European Heart Journal, 2012. 33: p. 794-794. 

 

434.Ohsawa, I., et al., Consumption of hydrogen water prevents atherosclerosis in apoliporotein E knockout mice. Biochem Biophys Res Commun, 2008. 377(4): p. 1195-8.
440.Wang, Y., et al., Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model. Respir Res, 2011. 12: p. 26. 

 

445.Yu, Y.S. and H. Zheng, Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats. Mol Cell Biochem, 2012. 365(1-2): p. 233-42. 

 

446.Zheng, H. and Y.S. Yu, Chronic hydrogen-rich saline treatment attenuates vascular dysfunction in spontaneous hypertensive rats. Biochemical Pharmacology, 2012. 83(9): p. 1269-77. 

 

484.Watanabe, T., Y. Kishikawa, and W. Shirai, Influence of alkaline ionized water on rat erythrocyte hexokinase activity and myocardium. J Toxicol Sci, 1997. 22(2): p. 141-52. 

 

485.Watanabe, T. and Y. Kishikawa, Degradation of myocardiac myosin and creatine kinase in rats given alkaline ionized water. J Vet Med Sci, 1998. 60(2): p. 245-50. 

 

487.Watanabe, T., et al., Histopathological influence of alkaline ionized water on myocardial muscle of mother rats. J Toxicol Sci, 1998. 23(5): p. 411-7.

   

 

 

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